For people with Psoriasis
Diprobase Cream contains white soft paraffin and liquid paraffin, known to help prevent water evaporating from the skin surface. Water evaporation is increased in psoriatic lesions compared with normal skin (1).
The experts at HelloSkin were unable to find clinical data on the benefits of Diprobase Cream Emollient specifically on psoriatic lesions.
For people with Eczema
In people with atopic dermatitis, Diprobase cream has been shown to increase skin hydration and to transiently reduce water evaporation from the skin surface (2).
The product contains yellow soft paraffin and liquid paraffin, known to help prevent water evaporating from the skin surface. In atopic dermatitis, water loss from the upper skin layer is linked to a reduced skin barrier function (3).
This reduced barrier function makes the skin more susceptible to external environmental triggers which aggravates the condition and leads to further itching, scratching and inflammation (4).
In the study mentioned above they were unable to demonstrate a persistent effect on barrier function after using Diprobase Cream for 28 days (2). A study on the efficacy of Diprobase Cream in infants with eczema is ongoing (5).
- Ann Dermatol. 2012 May; 24(2): 168–174
- J Dermatol. 2016 Apr 21. doi: 10.1111/bjd.14684
- Am J Clin Dermatol. 2003;4(11):771-88
- Am Fam Physician. 2012 Jul 1;86(1):35-42
- Trials. 2015 Jul 15;16:304