Creams are thicker and greasier than lotions. Creams are easy to spread over sore skin, are quickly absorbed into the skin, and do not stain clothes. Many people prefer creams for daytime use. Because of their relatively high lipid content, creams can be a good daytime choice to help manage dry skin. To be most effective, creams should be reapplied every 3-4 hours if possible, or when your skin feels dry. Creams are often the preferred choice for day-to-day use.